Genome Scale Comes From Repeated Readout

Instrument Days Scale

repeated readout reaches a target

Genome-scale evidence comes from repeated physical readout budgets. Exact arithmetic here means exact results for the stated model inputs; measured inputs still carry uncertainty and significant-figure limits.

highlighted = computed this step

Instrument days multiply readout

With 2 instruments and 3 runs per day, the readout budget is 12000 bases per day.

Bday=2⋅3⋅2000=12000B_{\text{day}}=2\cdot3\cdot2000=12000
Indexed throughputIndexed measurements become exact count budgets.run outputday outputindexed readout

Target divided by daily output gives days

A 24000 base training target takes 2 days. These are toy values, not historical Human Genome Project logistics.

D=2400012000=2D=\frac{24000}{12000}=2
Indexed throughputIndexed measurements become exact count budgets.run outputday outputindexed readout