Holding signal fixed isolates the half-signal constant in the occupancy ratio. Exact arithmetic here means exact results for the stated model inputs; measured inputs still carry uncertainty and significant-figure limits.

highlighted = computed this step

Half-signal four gives three fourths bound

Hold signal at 12. Half-signal 4 gives occupancy 3/4.

12/(12+4)=3412/(12+4)=\frac{3}{4}
Receptor occupancy ledgerA half-signal constant turns signal into a bound fraction.123/4

Half-signal six gives two thirds bound

Half-signal 6 gives occupancy 2/3 with the same signal.

12/(12+6)=2312/(12+6)=\frac{2}{3}
Receptor occupancy ledgerA half-signal constant turns signal into a bound fraction.122/3

Half-signal twelve gives one half bound

When half-signal equals the signal, the toy occupancy is 1/2. This is a ratio check, not receptor chemistry.

12/(12+12)=1212/(12+12)=\frac{1}{2}
Receptor occupancy ledgerA half-signal constant turns signal into a bound fraction.121/2